2019-01-07
A Viedma ripening route to an enantiopure building block for Levetiracetam and Brivaracetam
Publication
Publication
Org. Biomol. Chem , Volume 17 - Issue 1 p. 35- 38
A simple asymmetric synthesis route to the chiral component of the anti-epileptic drugs Levetiracetam and Brivaracetam has been developed. This approach is based on the rational design and application of a Viedma ripening process. The practical potential of the process is demonstrated on a large scale.
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| RSC | |
| doi.org/10.1039/C8OB02660B | |
| Org. Biomol. Chem | |
| Organisation | Self-Organizing Matter |
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Baglai, I., Leeman, M., Kellogg, R., & Noorduin, W. (2019). A Viedma ripening route to an enantiopure building block for Levetiracetam and Brivaracetam. Org. Biomol. Chem, 17(1), 35–38. doi:10.1039/C8OB02660B |
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