Herein we introduce a “chiral switch” – a sequence of operations that alternate between equilibrium and non-equilibrium conditions to switch the absolute configuration of a chiral center. The generality and practical potential of the technique are demonstrated with three unnatural α-amino acid precursors.

Additional Metadata
Keywords Materials Chemistry, Electronic, Optical and Magnetic Materials, General Chemistry, Surfaces, Coatings and Films, Metals and Alloys, Ceramics and Composites, Catalysis
Publisher RSC
Persistent URL
Journal Chem. Commun.
Baglai, I, Leeman, M, Kaptein, B, Kellogg, R.M, & Noorduin, W.L. (2019). A chiral switch: balancing between equilibrium and non-equilibrium states. Chem. Commun., 55(48), 6910–6913. doi:10.1039/c9cc03250a