2020-02-07
Impact of crowders on the morphology of bacterial chromosomes
Publication
Publication
EPL (Europhysics Letters) , Volume 128 - Issue 6 p. 68003: 1- 7
Inspired by recent experiments on the effects of cytosolic crowders on the organization of bacterial chromosomes, we consider a "feather-boa" type model chromosome in the presence of non-additive crowders, encapsulated within a cylindrical cell. We observe spontaneous emergence of complementary helicity of the confined polymer and crowders. This feature is reproduced within a simplified effective model of the chromosome. This latter model further establishes the occurrence of longitudinal and transverse spatial segregation transitions between the chromosome and crowders upon increasing the crowder size.
| Additional Metadata | |
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| IOP | |
| The Netherlands Organisation for Scientific Research (NWO) | |
| doi.org/10.1209/0295-5075/128/68003 | |
| EPL (Europhysics Letters) | |
| Organisation | Theory of Biomolecular Matter |
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Kumar, A., Swain, P., Mulder, B., & Chaudhuri, D. (2020). Impact of crowders on the morphology of bacterial chromosomes. EPL (Europhysics Letters), 128(6), 68003: 1–7. doi:10.1209/0295-5075/128/68003 |
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