We present techniques based on optical trapping of micron-sized particles as probes and detecting their motion with sub-nanometer accuracy at 100 kHz bandwidth that can measure viscoelastic properties of biomaterials and cells on micrometer scales.

Optical Society of America
Biological Soft Matter-Former Group

Mizuno, D., Atakhorrami, M., Addas, K. M., Tang, J. X., Koenderink, G., MacKintosh, F., & Schmidt, C. F. (2008). Laser trapping and laser interferometry for high-bandwidth micromechanical probing of biomaterials. In Asia Optical Fiber Communication and Optoelectronic Exposition and Conference, OSA Technical Digest : conference October 30 - November 2, Shanghai, China.