We present techniques based on optical trapping of micron-sized particles as probes and detecting their motion with sub-nanometer accuracy at 100 kHz bandwidth that can measure viscoelastic properties of biomaterials and cells on micrometer scales.

Optical Society of America
Biological Soft Matter-Former Group

Mizuno, D, Atakhorrami, M, Addas, K M, Tang, J X, Koenderink, G.H, MacKintosh, F.C, & Schmidt, C.F. (2008). Laser trapping and laser interferometry for high-bandwidth micromechanical probing of biomaterials. In Asia Optical Fiber Communication and Optoelectronic Exposition and Conference, OSA Technical Digest : conference October 30 - November 2, Shanghai, China. Optical Society of America.