Dissecting spindle architecture with a laser
Cell , Volume 149 - Issue 3 p. 507- 509
Microtubules in spindles are too dense to resolve by light microscopy, even with super-resolution methods. Using a new method based on laser-ablation techniques, Brugue´ s et al. present the first quantitative characterization of the vertebrate meiotic spindle and propose an assembly mechanism for building this architecture.