Canalization of C. elegans Vulva Induction against Anatomical Variability
It is not understood how development occurs with astounding reproducibility despite variability on the cellular level. We show how a feedback mechanism involving cell signaling and migration generates an invariant cell fate pattern in C.elegans vulva development, even though anatomical variability causes strong initial variation in cell fate induction.
|Publisher||Elsevier/ Cell Press|
|Funder||ERC , NWO|
Huelsz-Prince, G, & van Zon, J.S. (2017). Canalization of C. elegans Vulva Induction against Anatomical Variability. Cell Systems, 4, 219–230. doi:10.1016/j.cels.2017.01.009