We formulate, implement and test a robust method of determining sphere size distributions from finite thickness planar sections. The method uses a forward approach in which populations of proposed distributions are tested against the input data and refined using a genetic algorithm. This method is then applied to a real-world data set concerning endo- and exocytotic vesicles in the apical region of tip growing pollen tubes of Arabidopsis thaliana.

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Persistent URL dx.doi.org/10.1111/j.1365-2818.2008.02032.x
Journal J. Microsc.
de Nooijer, S, Ketelaar, T, & Mulder, B.M. (2008). Sphere size distributions from finite thickness sections: a forward approach employing a genetic algorithm. J. Microsc., 231, 257–264. doi:10.1111/j.1365-2818.2008.02032.x