We review recent progress in the study of the structure and dynamics of phospholipid membranes and associated proteins, using novel label-free analytical tools. We describe these techniques and illustrate them with examples highlighting current capabilities and limitations. Recent advances in applying such techniques to biological and model membranes for biophysical studies and biosensing applications are presented, and future prospects are discussed.

Chem. Soc. Rev.

Mashaghi, A., Mashaghi, S., Reviakine, I., Heeren, R., Sandoghdar, V., & Bonn, M. (2014). Label-free characterization of bio-membranes : from structure to dynamics. Chem. Soc. Rev., 43(3), 887–900. doi:10.1039/C3CS60243E